About ARGPRISM

ARGPRISM-DB (Antibiotic Resistance Genes Database) is a curated, literature-backed database focused on antibiotic resistance genes (ARGs) in pathogenic microorganisms. The database was developed to address the urgent need for a centralized resource that consolidates information on ARGs and the drugs they confer resistance to. ARGPRISM-DB aggregates data from authoritative sources such as the Comprehensive Antibiotic Resistance Database (CARD), UniProt, ResFinder, HMD-ARG-DB, DeepARG-DB, SARG and other peer-reviewed resources, providing researchers with comprehensive insights into the genetic factors driving antibiotic resistance.

ARGPRISM-DB compiles data from published studies identifying specific ARGs associated with various pathogens and the drugs that these genes render ineffective. Each entry is meticulously curated and supported by peer-reviewed literature, ensuring the highest standard of accuracy and relevance. The database includes key metadata, such as the consolidated database, gene name, the associated resistance drug(s), and sequence length ranges. The custom naming conventions applied to each entry facilitate easy downstream analysis and integration with other research tools.

With ARGPRISM-DB, researchers have access to an invaluable resource for exploring antibiotic resistance, identifying ARGs linked to drug resistance, and advancing the development of strategies to combat the global threat of antimicrobial resistance.